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TNF-α在抗感染中的作用 被引量:25

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摘要 肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)是一种多肽类细胞因子,主要由激活的单核巨噬细胞合成分泌,多以自分泌或旁分泌方式作用于靶细胞而引起广泛的生物学效应。其抗感染的机制比较复杂,可以通过调节黏附因子的表达而促进中性粒细胞募集发挥抗真菌与细菌的感染作用,也可以诱导病毒感染细胞的凋亡而抑制病毒增殖。本文就TNF-α在抗感染中的作用研究进展作一综述。
作者 华锋 刘金辉
出处 《南昌大学学报(医学版)》 CAS 2012年第5期96-99,共4页 Journal of Nanchang University:Medical Sciences
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