摘要
目的:探讨藤茶蛇葡萄素(APS)的体外抗肿瘤作用。方法:采用MTT法观察APS对人卵巢癌细胞SK-OV-3和人恶性黑色素瘤A375细胞抑制作用。结果:APS能明显抑制体外培养的SK-OV-3、A375细胞的生长。MTT结果显示,APS对SK-OV-3细胞的IC50为24.24μg/ml;对A375细胞的IC50为18.29μg/ml。结论:APS对体外SK-OV-3、A375细胞的生长均有明显的抑制作用。
Objective： To study the in vitro anti-tumor effect of ampelopsis （APS）. Methods： The inhibitory effect of APS on the human ovarian cancer cell SK-OV-3 and human malignant melanoma cell A375 was observed using MTT. Results ： The growth of SK-OV-3 and A375 cultured in vitro was inhibited significantly by APS. The result of MTT showed that the IC50 of APS for SK-OV-3 and A375 was 24.24 μg/ml and 18.29 μg/ml, respectively. Conclusions： APS may significantly inhibit the growth of SK-OV-3 and A375 cell＇ s in vitro.
出处
《广西中医药》
2009年第1期46-48,共3页
Guangxi Journal of Traditional Chinese Medicine
基金
广西自然科学基金(桂科基0639052)
