摘要
目的探讨C-反应蛋白(CRP)升高在老年冠心病患者中的临床意义。方法空腹外周血取自老年冠心病患者70例,其中急性冠脉综合征(ACS)45例(包括急性心肌梗死22例和不稳定型心绞痛23例),稳定型心绞痛(SAP)25例,以及非冠心病对照组30例。采用速率散射比浊法测定血清CRP水平。结果ACS组血清CRP水平为(17.68±6.32)mg/L,显著高于SAP组和对照组([5.46±4.73)mg/Land(3.58±2.87)mg/L,P<0.05]。稳定型心绞痛组与对照组之间CRP水平差异无统计学意义,急性心肌梗死组与不稳定型心绞痛组比较差异有统计学意义(P<0.01)。结论血清CRP水平可作为老年急性冠脉综合征患者的临床辅助监测指标。
Objective To explore the changes of C-reactive protein （CRP） in senior patients with acute coronary syndrome （ACS） and the significance of elevated CRP level in pathogenesis of ACS. Methods Peripheral blood samples were collected from 70 coronary artery disease （CAD） patients, 54 males and 16 females, aged （67.8±12.4） （65-88）, 45 with ACS and 25 with stable angina pectoris （UAP）. The 45 ACS patients included 22 cases of acute myocardial infarction （AMI） and 23 cases of unstable angina pectoris （UAP）. Thirty persons without CAD were used as controls. Ratenephelometry was used to measure the CRP level. Results The CRP level of the ACS group was （17.68± 6.32） mg/L, significantly higher than those of the SAP group and control group [（ 5.46±4.73 ） mg/L and （ 3.58 ±2.87 ） mg/L respectively, both P〈0.05 ]. The CRP level of the AMI patients was （24.18±12.3）mg/L, significantly higher than that of the UAP patients [（11.38± 6.96）mg/L, P〈0.01]. Conelusion CRP level can be used as an index for evaluating the existence of ACS.
出处
《中国急救复苏与灾害医学杂志》
2008年第11期666-667,共2页
China Journal of Emergency Resuscitation and Disaster Medicine
