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急性心肌梗死早期血浆脑钠肽水平与梗死部位及左室功能和重塑的关系 被引量:9

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摘要 目的:探讨急性心肌梗死(AMI)早期血浆脑钠肽(BNP)水平与不同部位梗死急性期及6个月左室功能及重塑的关系。方法:486例AMI患者分为:A组,前、侧壁组,B组:下、后壁组;根据BNP是否大于180 ng/L将A、B 2组分别分为A1组、B1组(≥180 ng/L),A2组、B2组(<180 ng/L)。所有患者,均急诊行冠状动脉介入治疗及左室造影检查,记录左室功能及左室重塑参数,6个月后复查。结果:急性期A组室壁运动障碍较B组明显,室壁瘤比率高;A1组心功能指标及左室室壁运动积分(LVWMS)均差于A2组;B1组LVWMS高于B2组。术后6个月复查,A1组左室功能及室壁运动改善情况均差于其余3组,B2组改善最明显。AMI早期BNP浓度与左室射血分数呈负相关,6个月后复查,A组中二者仍呈负相关。结论:AMI早期BNP浓度对于梗死心功能状态及心室重构有重要的预测作用,尤其是前壁心肌梗死这种作用可持续到心肌梗死后6个月。
出处 《临床心血管病杂志》 CAS CSCD 北大核心 2008年第10期792-794,共3页 Journal of Clinical Cardiology
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参考文献8

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