摘要
背景与目的:肝局灶性结节增生(focal nodular hyperplasia,FNH)是肝脏少见的良性肿瘤样病变,其影像学诊断仍有困难。本研究拟探讨FNH的MRI动态增强和数字减影血管造影(digital subtraction angiography,DSA)表现,以提高FNH影像学诊断水平。方法:回顾分析30例经病理证实的FNH的MRI和DSA影像资料。MRI检查26例,其中,平扫后普通增强扫描11例,动态增强扫描15例;DSA检查10例。结果:MRI动态增强扫描15例18个病灶动脉期呈显著强化,强化持续至延迟期仍高于或等于肝实质。11个病灶显示中央瘢痕。中央瘢痕在门脉期开始强化并持续至延迟期。动态增强时间-信号强度曲线18个病灶均为动脉期迅速升高,门脉期至延长期缓慢下降,呈速升-缓降型。DSA检查10例13个病灶表现为动脉血供丰富,8个病灶供血动脉分支进入病灶后呈辐射状向周围发散。结论:MRI动态增强扫描更能敏感显示FNH中央瘢痕组织信号。FNH的动态增强时间-信号强度曲线特征表现为速升-缓降型。FNH的DSA特征为供血动脉分支进入病灶后呈辐射状向周围发散。MRI动态增强和DSA检查可提高FNH诊断的准确率。
BACKGROUND ＆ OBJECTIVE： Focal nodular hyperplasia （FNH） is a rare benign hepatic tumor and its imaging diagnosis remains difficult. This study was to analyze dynamic contrast-enhanced MR imaging and digital subtraction angiography （DSA） manifestation of FNH, and to improve the diagnostic accuracy of FNH. METHODS. The MRI and DSA imaging data of 30 patients with FNH proved by pathology were reviewed. Conventional contrast-enhanced MRI was completed in 11 patients; dynamic contrast-enhanced MRI was completed in 15 patients. DSA was completed in 10 patients. RESULTS. On dynamic contrast-enhanced MRI scan, 18 lesions in 15 patients showed obvious enhancement at arterial phase and prolonged enhancement at delayed phase. Central scars were found in 11 lesions, and showed enhancement since portal vein phase till delayed phase. The timesignal intensity curves of the 18 lesions were ascended rapidly at arterial phase, and descended slowly at portal vein phase and delayed phase. On DSA examination, 13 lesions in the ten patients showed dilated feeding arteries, and radiate feeding arterial branches were seen in eight lesions. CONCLUSIONS： Dynamic contrast-enhanced MRI can fully show abnormal signal of the central scar of FNH. The time-signal intensity curve of FNH ascends rapidly and descends slowly. On DSA imaging, the feeding arteries of FNH spread radially. Dynamic contrast-enhanced MRI and DSA could improve the diagnostic accuracy of FNH.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
2008年第11期1186-1189,共4页
Chinese Journal of Cancer
关键词
肝肿瘤
局灶性结节增生
诊断
磁共振成像
血管造影
Liver neoplasm
Focal nodular hyperplasia
Diagnosis
Magnetic resonance imaging
Digital subtraction angiography
