摘要
背景与目的:肝脏瘤样病变是一类肝脏良性病变,其中以局灶性结节性增生(focalnodularhyperplasia,FNH)、炎性假瘤(inflammatorypseudotumor,IPT)、腺瘤性结节性增生、局灶性脂肪变较为多见,易与原发性肝癌相混淆。本文旨在探讨这4种瘤样病变的临床特点与治疗方法。方法:对12年来中山大学肿瘤防治中心确诊的4种肝脏瘤样病变共70例的临床及随访资料进行分析和总结。结果:34例(48.6%)瘤样病变的患者有临床症状,以腹部隐痛为主。手术前检查乙型肝炎病毒抗原阳性22例(31.4%);肝功能轻度异常21例;甲胎蛋白>25μg/L6例。瘤样病变的B超及CT表现多种多样,仅8例FNH术前能确诊。61例瘤样病变行手术切除,术后无并发症。随访发现1例FNH及1例IPT复发。复发后采用非手术方式治疗效果好。结论:肝脏瘤样病变容易与原发性肝癌相混淆,性质不明者应手术探查。
BACKGROUND ＆ OBJECTIVE. Focal nodular hyperplasia （FNH）, inflammatory pseudotumor （IPT）, adenomatous nodular hyperplasia （ANH）, and focal fatty change （FFC） are common hepatic tumor-like lesions, a group of benign liver diseases, which remains difficult to be distinguished from primary liver cancer （PLC）. This study was to investigate the clinical features and treatment of these 4 kinds of hepatic tumor-like lesions, METHODS- Clinical data of 70 patients with pathologically conformed hepatic tumor-like lesions, treated in Cancer Center of Sun Yat-sen University from 1992 to 2004, were studied retrospectively. RESULTS. Of the 70 patients, 34 （48.6%） had clinical symptoms, and most of them suffered mild pain in the abdomen; 22 （31.4%） were positive for hepatitis B virus （HBV） antigen; 21 had mild abnormal liver function; 6 had alpha fetal protein （AFP） 〉 25 μg/L. The ultrasonography and computed tomography （CT） presentations of the tumor-like lesions were various. Only 8 cases of FNH were diagnosed preoperatively. Sixty-one patients received resection, with no postoperative complication occurred. One case of FNH and 1 case of IPT were recurred during follow-up, and treated with non-resection therapy. CONCLUSIONS： Hepatic tumor-like lesions are difficult to be distinguished from PLC. Exploratory operation should be performed in cases suspicious of PLC.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
2006年第3期352-354,共3页
Chinese Journal of Cancer
关键词
肝肿瘤
瘤样病变
临床特点
诊断
治疗
Liver neoplasms
Tumor-like lesion
Clinical features
Diagnosis
Treatment
