摘要
基因系尾型同源盒基因(CDX2)尾型同源框转录因子2,是一种新发现的特异性的核转录因子,属于果蝇尾部相关同源框基因家族成员,不仅控制着胚胎细胞的发育和分化,而且在成人组织的分化和增殖调控中起着重要作用。新的研究发现,消化道、泌尿生殖、妇科、头颈部等部位均有CDX2表达。本文就CDX2基因的研究现状予以综述。
CDX2 is a Drosophila caudal-related homeobox transcription factor which is a new found specific nuclear factor（NF） belonging to the family of drosophila caudal-related homeobox gene. It not only controls the development and differentiation of embryonic cell,but also plays an important role in regulating the differentiation and proliferation of adult tissue. Recent studies found that CDX2 gene had expression in many tissues, such as digestive tract, genitourinary tracts,, head and neck. and so on. This article reviews the progress of CDX2 gene.
出处
《医学综述》
2008年第21期3221-3224,共4页
Medical Recapitulate
关键词
基因系尾型同源盒基因
肠化生
肿瘤
Caudal-related homeobox transcription factor 2
Intestinal metaplasia
Tumor
