摘要
[目的]探讨血清C-反应蛋白、IL-6浓度与脑梗死的关系。[方法]对96例脑梗死患者及50例正常对照者血清采用免疫比浊法测定CRP水平,采用酶联免疫吸附双抗体夹心法测定IL-6水平,并与病情进行相关分析。[结果]脑梗死组血清CRP、IL-6水平明显高于正常对照组(P﹤0.01),脑梗死组不同分型间血清CRP、IL-6水平比较:重型组高于中型组、轻型组,差异均有统计学意义(P﹤0.05)。不同组间CRP、IL-6水平成正相关(r=0.52,P﹤0.01)。脑梗死不同预后组显著进步组、进步组明显低于无变化组、死亡组(P﹤0.05)。[结论]CRP、IL-6是导致脑梗死的危险因素,是临床评价脑梗死严重程度和预后的重要指标。
[Objective] To explore the relationship between serum C-reactive protein （CRP）, IL-6 and cerebral infarction. [Methods] Serum C-reactive protein levels in 96 patients with cerebral infarction and 50 normal controls were determined. We analyzed the relationship between the serum C-reaction protein levels and severity of disease as well as outcome. [Results] The serum levels of CRP, IL-6 in patients significantly raised above normal control （P〈 0.01）. CRP, IL-6 levels in the patients with serious condition were higher than those of the patients with middle and light conditions, there was significant difference （P 〈 0.05）. CRP, IL-6 levels had positive correlations in different groups （r = 0.52, P 〈 0.01）. [Conclusion] CRP, IL-6 are dangerous factors to lead to cerebral infarction, they are the important indices to valuate the serious levels and prognosis in patients with cerebral infarction.
出处
《现代预防医学》
CAS
北大核心
2008年第21期4291-4292,共2页
Modern Preventive Medicine
关键词
CRP
IL-6
脑梗死
预后
C-reactive protein
IL-6
Cerebral infarction
Prognosis
