期刊文献+

多中心随机对照评价中医药治疗小儿病毒性肺炎风热闭肺证、痰热闭肺证临床疗效 被引量:10

Evaluation of TCM on children's respiratory syncytial virus pneumonia with "wind and heat blocking the lung syndrome" and "phlegm-heat obstructing the lung syndrome" by multi-center stratified randomization and equal control methods
原文传递
导出
摘要 目的客观评价中医药治疗小儿病毒性肺炎风热闭肺证、痰热闭肺证的临床疗效。方法采用单盲、多中心、分层区组随机、平行对照的方法,对5家医院的297例风热闭肺证、痰热闭肺证病毒性肺炎患儿进行临床研究,治疗组静脉滴注清开灵注射液,其中痰热闭肺证口服儿童清肺口服液、风热闭肺证口服小儿咳喘灵口服液;对照组静脉滴注利巴韦林注射液,口服复方愈创木酚磺酸钾口服液(伤风止咳糖浆),疗程均为10d。结果两组主症终点积分值、治疗前后主症积分差值比较差异均有高度统计学意义(P<0.01),治疗组显著优于对照组,尤其表现在痰热闭肺证上。在发热、咳嗽、痰壅、肺部啰音恢复的起效时间上比较,治疗组起效时间显著早于对照组,差异有高度统计学意义(P<0.01)。治疗组愈显率90.54%,对照组81.88%,差异有统计学意义(P<0.05),治疗组综合疗效优于对照组;痰热闭肺证治疗组愈显率88.89%,对照组80.62%,差异有统计学意义(P<0.05),治疗组优于对照组;风热闭肺证治疗组愈显率95.00%,对照组84.31%,差异无统计学意义(P>0.05)。根据治疗前后主症积分的减少情况对疾病进行疗效再评价,结果治疗组愈显率87.84%,对照组65.77%,差异有高度统计学意义(P<0.01),治疗组显著优于对照组;痰热闭肺证治疗组愈显率91.67%,对照组64.29%,差异有高度统计学意义(P<0.01),治疗组显著优于对照组;风热闭肺证治疗组愈显率77.50%,对照组68.63%,差异无统计学意义(P>0.05)。结论中医药治疗小儿病毒性肺炎疗效显著,尤其表现在痰热闭肺证的治疗上。 Objective To evaluate curative effect of TCM objectively on children's respiratory syncytial virus pneumonia with "wind and heat blocking the lung syndrome" and "phlegm-heat obstructing the lung syndrome ". Methods Single blind, multi-center, stratified randomization and equal control methods were used on 297 cases of RSV pneumonia with "wind and heat blocking the lung syndrome" and "phlegm-heat obstructing the lung syndrome" in five centers hospitalization who were observed and treated by Chinese medicine or western medicine. In the control group, the patients were treated by Ribavilin Injection and Compound guaiacol potassium sulfonale Oral Solution; In the test group, Qingkailing Injection and Ertongqingfei Oral Solution were used for patients with "wind and heat blocking the lung syndrome", and Qingkailing Injection and Xiaoerkechuanling Oral Solution for "phlegm-heat obstructing the lung syndrome". The time of therapy was 10 days for each group. Reults The score of primary symptoms at post-treatment and the score diminishment between pre-treattnent and post-treatment in the test group, especially in the group with the "phlegm-heat obstructing the lung syndrome", were better than those in the control group(P 〈0.01 ). The symptom recovery in fever, cough, sputum and auscultation on the lung of the test group were much earlier than that of the controlled group (P 〈0.01 ). The total effective rates evaluated by disease and score's diminution of primary symptoms were 90.54% and 87. 84% in the test group, and were 81. 88% and 65.77% in the control group, both with significant differences between two gruops(P 〈0.05, P 〈0.01 ). At the same points for the "wind and heat blocking the lung syndrome", the total effective rates were 88.89% and 91.67% in the test group, and were 80.62% and 64.29% in the control group, both with significant differences between two gruops ( P 〈 0.05, P 〈 0.01 ) ; and for the "wind and heat blocking the lung syndrome", they
出处 《北京中医药大学学报》 CAS CSCD 北大核心 2008年第9期629-633,642,共6页 Journal of Beijing University of Traditional Chinese Medicine
基金 国家"十五"科技攻关计划项目(No.2004BA716B03)
关键词 小儿病毒性肺炎 风热闭肺证 痰热闭肺证 中医药 多中心随机对照 Children's respiratory syncytial virus pneumonia wind and heat blocking the lung syndrome phlegm-heat obstructing the lung syndrome traditional Chinese medicine Multi-center stratified randomization and equal control
  • 相关文献

参考文献4

二级参考文献8

共引文献122

同被引文献80

引证文献10

二级引证文献59

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部