摘要
采用双抗体夹心ELISA法对32例脑星形胶质瘤患者和45例正常对照血清可溶性白细胞介素2受体（SIL－2R）水平进行检测，其中21例患者于术后1个月进行复查。结果显示脑星形胶质瘤组血清SIL－2R水平明显高于正常对照组，血清SIL－2R水平变化与肿瘤病理级别密切相关，术后1个月血清SIL－2R水平显著降低。上述结果提示血清SIL－2R水平变化与脑星形胶质瘤消长密切相关，检测SIL－2R对判断脑星形胶质瘤病理级别及预后有一定的临床参考价值。
Objective To explore the pathogenetic role of soluble interleukin-2 receptor (sIL-2R)and its clinical significance in astrocytomas. Methods The serum slL-2R levels were measured in 32 patients with astrocytomas and 45 normal controls (NC) by ELISA. 21 of 32 patients with astrocytomas were measured again after one month of poetoperation. Results The serum sIL-2R level of astrocytomas group was much higher than that of NC group. The serum sIL-2R levels correlated with the stages of astrocytomas. The serum sIL-2R levels of patients with astrocytomas were decreased obviously after one month of postoperation.Conclusions The variation of serum sIL-2R levels correlate with growth and disappearance of astrocytomas. The determination of serum slL-2R levels is much useful in determining the stages and prognosis of astrocytomas.
出处
《中国神经免疫学和神经病学杂志》
CAS
1997年第4期203-205,共3页
Chinese Journal of Neuroimmunology and Neurology
