摘要
目的探讨乳腺癌患者妊娠次数与腋窝淋巴结转移之间的关系。方法171例乳腺癌患者按妊娠次数分为妊娠1次,2次及2次以上共3组。统计该3组患者各自发生腋窝淋巴结转移的患者比例及发生转移的腋窝淋巴结在所检测的淋巴结中的比例,应用χ2检验分析不同组别间腋窝淋巴结转移阳性患者比例的差异,阳性转移淋巴结比例之间的差异,从而探讨乳腺癌患者的妊娠次数与其腋窝淋巴结转移例数及转移个数之间的关系。结果妊娠1次、妊娠2次及妊娠2次以上组发生腋窝淋巴结转移的比例分别为34.78%、50%、64.10%。随妊娠次数增加,发生腋窝淋巴结转移的比例逐渐增高。其中妊娠2次以上患者组发生腋窝淋巴结转移的比例明显高于妊娠1次患者组发生腋窝淋巴结转移的比例(64.10%vs34.78%),2者相比差异有显著性(P=0.012)。妊娠1次、妊娠2次及妊娠2次以上组腋窝淋巴结发生转移的比例分别为44.58%、44.18%、52.97%。妊娠2次以上患者组腋窝淋巴结发生转移的比例明显高于妊娠2次患者组腋窝淋巴结发生转移的比例(52.97%vs44.18%),2者相比差异有显著性(P=0.025)。但妊娠1次组腋窝淋巴结发生转移的比例与妊娠2次组及妊娠2次以上组相比,差异均无显著性(P=0.948,P=0.167)。结论妊娠次数较少的患者组发生腋窝淋巴结转移的比例相对较小,发生转移的腋窝淋巴结数目也相对较少。乳腺癌患者的妊娠次数与乳腺癌的腋窝淋巴结转移有关。乳腺癌患者的妊娠次数对判断乳腺癌患者的腋窝淋巴结转移有一定的意义。
Objective To explore the relationship between the number of pregnancy and axillary lymph node metastasis in cases with breast carcinoma. Methods One hundred and seventy - one cases with breast carcinoma were divided into three groups according to the number of pregnancy：single pregnancy group, twice pregnancy, more than twice pregnancy group. The rates of the cases with positive axillary lymph node metastasis in every group and the rates of the lymph node with tumor metastasis in all tested lymph nodes in respective group were calculated. To explore the relation- ships between the number of pregnancy and the cases with axillary lymph node metastasis, the number of lymph node with tumor metastasis in cases with breast carcinoma, the differences of the rate of cases with axillary lymph node metastasis and the differences of the rate of positive lymph node metastasis,in different groups were analyzed by X2 test. Re- suits The rate of the cases with positive axillary lymph node metastasis in single pregnancy group, twice pregnancy group, more than twice pregnancy group was 34.78% ,50% ,64.10% respectively. The rate rose with the increase of the number of pregnancy. The rate of cases with axillary lymph node metastasis in more than twice pregnancy group was higher than that in single pregnancy group and there was distinct difference between the two group（64.10% vs 34.78%, P =0.012）. The rate of the lymph node with tumor metastasis in all tested lymph nodes in single pregnancy group, twice pregnancy group, more than twice pregnancy group was 44.58% ,44.18% ,52.97% respectively. The rate of the lymph node metastasis in all tested lymph nodes in more than twice pregnancy group was higher than that in twice pregnancy group and there was distinct difference between the two group（52.97% vs 44.18% ,P =0.025）. But the difference between other groups were indistinct （P = 0. 948, P = 0.167）. Conclusions The rate of the cases with positive axillary lymph node metastasis is low in the group with less pregnancy numbe
出处
《医学信息（手术学分册）》
2008年第7期594-596,604,共4页
Medical Information Operations Sciences Fascicule
关键词
乳腺癌
妊娠次数
腋窝淋巴结转移
breast carcinoma
number of pregnancy
axillary lymph node metastasis
