摘要
目的探讨腔隙性脑梗死(LI)患者事件相关电位P300变化及P300电位与病灶多少间的关系。方法记录40例腔隙性脑梗死患者和40例健康对照者的P300电位。比较两组P300电位及单病灶LI组和多病灶LI组P300电位的检测结果。结果研究组的事件相关电位P300内源性成分N2、P3潜伏期较对照组差异有统计学意义(P<0.01),波幅较对照组差异亦有统计学意义(P<0.01),多发病灶LI组P3潜伏期与单一病灶LI组比较差异有统计学意义(P<0.01),单波幅间差异无统计学意义(P>0.05)。结论腔隙性脑梗死患者认知功能存在损害,且多发病灶LI患者受影响更明显,P300电位可作为评价LI患者认知功能的指标。
Objective lacunar infarct （LI） in patients with event - related potential P300 and P300 potential changes and the relationship between the number of lesions. Methods Recorded 40 cases of lacunar infarct patients and 40 healthy people of the P300. Comparative study group and control group P300 potentials and Single - lesion LI group and multi - lesion LI group P300 potential characteristics. Results Research team event - related potential P300 endogenous components N2, P3 extended incubation period than the control group （ P 〈 0.01 ） lower volatility （ P 〈 0.01 ）, multi - lesions LI group than Single - lesion LI group extended incubation period （ P 〈0. 01 ）, the volatility did not change significantly （ P 〉0.05 ）. Conclusion lacunar infarction patients with cognitive function of the damage, and patients with multi -lesions LI affected more significantly, P300 potential can be used as evaluation of cognitive function in patients with LI indicators.
出处
《实用心脑肺血管病杂志》
2008年第9期17-18,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
