摘要
目的分析老年高血压合并血管性认知功能障碍（vascular cognitive impairment,VCI）患者的颈动脉粥样硬化及动态血压的特点。方法连续选择2015年6月～2016年5月在我院老年科接受住院治疗的46例老年高血压患者合并VCI作为VCI组，同时选取相同时间段就诊的仅患有原发性高血压的老年患者56例作为对照组，所有受试对象均采用简易智能状态检查量表（mini-mental state examination, MMSE）进行评分，并进行24h动态血压及颈动脉超声测定。结果VCI组合并斑块比例（97．8％VS64．3％，P=0．000）、24h收缩压[（137．95±14．86）mmHg vs （130.61±14．84）mmHg，1mmHg=0．133kPa，P=0．010]、日间收缩压[（138．02±14．50）mmHg vs （131．13±15．00）mmHg，P=0．020]、夜间收缩压[（137．31土17．52）mmHg7iS（129．45±17．58、mmHg，P=0．030]明显高于对照组，差异有统计学意义。结论颈动脉粥样硬化、血压增高是VCI的重要危险因素。
Objective To analyze the association between carotid atheroselerosis （AS） and ambula- tory blood pressure （ABP） in elderly hypertensive patients with vascular cognitive impairment （VCI）. Methods Forty-six elderly hypertensive patients with VCI admitted to our hospital from June 2015 to May 2016 served as a VCI group and 56 primary hypertensive patients served as a control group in this study. The patients were scored according to the MMSE Scale and their 24 h ABP was measured. Results The incidence of carotid artery plaques,24 h SBP,day and night SBP were significantly higher in VCI group than in control group （97. 8% vs 64. 3%,P=0. 000; 137.95±14.86 mm Hg vs 130.61±14.84 mm Hg,P=0. 010;138.02±14.50 mm Hg vs 131.13±15.00 mm Hg,P=0. 020;137. 31±17. 52 mm Hg vs 129.45±17.58 mm Hg,P=0. 030）. Conclusion Carotid AS and elevated BP are the important risk factors for VCI.
出处
《中华老年心脑血管病杂志》
CAS
2016年第12期1288-1290,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金
南京市医学科技发展项目(YKK14190)
关键词
认知障碍
脑血管障碍
颈动脉疾病
动脉粥样硬化
血压监测
便携式
cognition disorders
cerebrovascular disorders
carotid artery diseases
atherosclerosis blood pressure monitoring,ambulatory
