摘要
目的探讨白细胞介素-9(IL-9)、白细胞介素-13(IL-13)在支气管哮喘发病机制中的作用。方法用酶联免疫吸附法(ELISA)测定50例支气管哮喘急性发作期治疗前后患者和21例健康对照者的血清IL-9I、L-13的浓度。结果支气管哮喘急性发作期患者的血清IL-9、IL-13浓度显著高于正常对照组。结论IL-9、IL-13等炎性细胞因子的测定对于评价炎症程度及疗效、指导临床治疗有重要意义。
Objective It is to approach the actions of serum interleukin- 9 （IL- 9）, interleukin- 13 （IL- 13） levels in patients with bronchial asthma, Methods 50 patients with asthma and 21 cases of normal individuals were recruited into the study, The plasma levels of IL- 9, IL- 13 and IgE were assayed by ELISA, Results The serum levels of IL - 9, IL- 13 were remarkably increased in patients with asthma at the acute stage compared with healthy controls （P 〈 0.01 ）, Conclusion The detection of IL- 9, IL- 13 and other inflammatory cytokines is important to evaluate the extent and effect of inflammation, and to guide linical therapy,
出处
《现代中西医结合杂志》
CAS
2008年第27期4223-4224,共2页
Modern Journal of Integrated Traditional Chinese and Western Medicine
