摘要
目的:研究肾移植术后患者环孢素A(CsA)浓度与临床疗效之间的关系。方法:采用荧光偏振免疫法。结果:正常组分别与中毒组、排异组之间血药浓度有显著性差异。结论:环孢素A血药浓度监测必须结合临床,综合考虑各方面的因素,实现个体化给药。
Objective To study the relationship between the blood concentration of Cyclosporine A （CsA） and therapeutic efficacy in renal transplant recipients. Methods The serum concentrations of were determined dynamically with fluorescence polarization immunoassay in 33 patients. Results There were significant differences among the blood concentrations of Cyclosporin A in stable patients, patients with toxic manifestation and patients with rejection （ P 〈 0.01 ）. Conclusion Cyclosporine A （CsA） blood concentration monitoring is useful for individualization of treatment.
出处
《放射免疫学杂志》
CAS
2008年第4期354-355,共2页
Journal of Radioimmanology
关键词
肾移植
环孢素A
血药浓度监测
荧光偏振免疫法
kidney transplantation, cyclosporine A, blood drug concentration monitoring, FPIA
