摘要
目的探讨血管内皮因子（VEGF）在多发性骨髓瘤中的表达及其与疾病进展的关系。方法运用双抗体夹心ELISA的方法检测了32例多发性骨髓瘤患者VEGF、IL-6、IL-17的表达。结果与正常对照者（60．82±13．42）相比，多发性骨髓瘤患者（152．36±25．61）高表达VEGF（P〈0．01）。结论VEGF表达与多发性骨髓瘤的发生进展密切相关。
Objective To explore the vascular endothelial growth factor（VEGF） expression and its clinical significance in multiple myeloma. Methods VEGF,IL -6,IL - 17 were measured by ELISA. Results Comparing with the normals, VEGF was overexpressed in multiple myeloma （P 〈 0, 01 ）. Conclusion The value of VEGF might be a biomarker of disease progression in multiple myeloma.
关键词
多发性骨髓瘤
血管内皮生长因子
Multiple myeloma Vascular endothelial growth factor
