摘要
目的:通过对比研究冠心病患者心率变异性和冠状动脉病变程度,探讨两者间是否存在联系,为诊断冠心病提供更多途径。方法:选取冠心病患者120例作为实验组,分别为SAP、UAP、STEMI和NSTEMI组,每组30例。选取健康体检者31例作为正常对照组。所有入选对象于入院后24h内行24h动态心电图检查,冠心病患者均接受选择性冠状动脉造影检查。采用SPSS13.0统计软件进行统计学分析。结果:随冠状动脉病变程度加重,反映交感神经系统功能的心率变异性指标SDNN、SDANN、SDNN Index等显著降低(P<0.05),而反映副交感神经系统功能的心率变异性指标rMSSD、pNN50则无显著变化。结论:心率变异性可作为一个无创伤性指标间接反映冠状动脉病变程度,为冠心病的临床诊断提供依据。
Objective To investigate the association of heart rate variability （HRV） and the severity of coronary artery lesions in coronary heart disease （CHD）. Methods A total of 120 patients with CHD （30 SA, 30 UA, 30 STEMI, and 30 NSTEMI） were randomly recruited in this study and 31 healthy individuals were used as control. All subjects received 24-hour dynamic electrocardiography with 24 hours of admission and those with CHD received additional coronary angiography. Statistical analyses were performed using the SPSS 13.0. Results With the increasing extent of coronary artery lesions, the HRV indices SDNN, SDANN, and SDNN-index reflecting the sympathetic nervous function were significantly declined （P 〈 0.05）, while no marked changes in the indices RMSSD and pNN50 reflecting the parasympathetic nervous function occurred. Conclusion HRV may be used as a noninvasive indicator for indirectly signaling the severity of coronary artery lesions, providing support for the clinical diagnosis of CHD.
出处
《实用医学杂志》
CAS
2008年第10期1720-1722,共3页
The Journal of Practical Medicine
关键词
冠状动脉疾病
心率变异性
冠状动脉病变
Coronary disease Heart rate variability Coronary artery lesion
