摘要
红曲霉可产生多种聚酮类次生代谢产物,主要包括红曲色素、莫那可林K和桔霉素。其中红曲色素广泛用于食品着色,莫那可林K用作降血脂的药物,而桔霉素则对脊椎动物包括人体有肾毒性。本文对这几类聚酮类次生代谢产物的生物合成途径、生物合成相关的聚酮合成酶等方面的研究进展进行了综述。
Monascus species have the ability to produce secondary metabolites of polyketides. Including Monascorubrin pigment,which has been widely used as a natural food-coloring agent for many kinds of foods; Monacolin K, which has been proven to have cholesterol-lowering effects; and Citrinin, which is moderately nephrotoxic to vertebrates including humans. The research advances of polyketides biosynthetic pathway and cloning of biosynthetic gene clusters for these polyketides were reviewed.
出处
《食品工业科技》
CAS
CSCD
北大核心
2008年第3期292-295,共4页
Science and Technology of Food Industry
基金
广东药学院课题(44943003)
