SLE患者妊娠中抗磷脂抗体与妊娠的关系被引量：2

Relationship between the pregnancy and the antiphospholipid antibody in systemic lupus erythematosus

导出

摘要系统性红斑狼疮（SLE）是累及全身多系统的自身免疫性疾病，好发于育龄期妇女。患者妊娠期间抗磷脂抗体滴度的变化是不良妊娠结局可能的危险因素。抗磷脂抗体与凝血失衡，缺陷胎盘的产生、补体激活以及相关蛋白间的交互作用等是导致母体和胎儿损伤的重要因素。 Systemic Lupus Erythrematosus （SLE） is a common autoimmune disease, affecting several organs. Women in childbearing years are frequently affected. Positive for antiphospholipid antibody is a probable risk factor to bad pregnancy outcome in pregnant woman with SLE. Antiphospholipid antibody, disequilibrium in blood clotting mechanism, placental defect and the interaction among them are important factors for the damage to patients and fetuses.

作者章群叶冬青(审校者)

机构地区安徽医科大学公共卫生学院流行病与卫生统计学系安徽医科大学公共卫生学院流行病与卫生统计学系

出处《国际免疫学杂志》 CAS 2008年第2期101-105,共5页 International Journal of Immunology

基金国家自然科学基金资助项目（30371247）

关键词系统性红斑狼疮抗磷脂抗体妊娠 Systemic lupus erythematosus Antiphospholipid antibody Pregnancy

分类号 R593.241 [医药卫生—内科学] R714.2 [医药卫生—临床医学]

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