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血液透析患者骨密度与骨保护素和核因子κB受体活化因子配体的关系 被引量:5

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摘要 核因子κB受体活化因子配体(RANKL)是近年来在肿瘤坏死因子配体超家族中发现的一种具有调控破骨细胞产生和活化作用的细胞因子。它与骨保护素(OPG)、核因子κB受体活化因子(RANK)的相互作用,能调节破骨细胞的活化和增殖,维持正常骨重建过程。在维持性血液透析(MHD)患者体内,多种因素使这一分子调控系统发生变化,造成骨代谢异常,从而影响到骨矿含量,即骨密度发生变化。
出处 《中华肾脏病杂志》 CAS CSCD 北大核心 2008年第1期58-59,共2页 Chinese Journal of Nephrology
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同被引文献94

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