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眼镜蛇毒细胞毒素抗肿瘤作用的研究及进展 被引量：1

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摘要 本文以近年来国内外相关文献为依据,对眼镜蛇毒细胞毒素的分离、理化性质及抗肿瘤方面的研究及进展进行了综述,并对细胞毒素的实用提出展望。
作者 罗格莲
机构地区 福建生物工程职业技术学院
出处 《海峡药学》 2007年第11期4-7,共4页 Strait Pharmaceutical Journal
关键词 眼镜蛇毒 细胞毒素 肿瘤
分类号 R969 [医药卫生—药理学]
  • 相关文献

参考文献40

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  • 2Comes A, Pallabi De, Dasgupta S C. Occurrence of a unique protein toxin from the Indian King Cobra ( OpHiopHagushannah ) venom [ J ] . Toxicom,2001,39(2-3) :363. 被引量：1
  • 3Aripov, T. F; Gasanov, S. E; Salakhutdinov, B. A; Rozenstein, I. A; Kamaev, F. G. Central Asian cobra venom cytotoxins-induced aggregation, permeability and fusion of liposomes [ J ] . Gen. physiol. BiopHys. 1989,8:359-474. 被引量：1
  • 4Chien,K. Y;Huang,W. N;Jean,J. H;Wu,W. G. Fusion of spHingomyelin vesicles induced by proteins from Taiwan cobra( Naja naja atrn) venom. Interactions of zwitterionic pHospHolipids with cardiotoxin analogues [ J }. J. Biol. Chem. 1991,266,3252-3259. 被引量：1
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  • 7Roumestand C,Gilquin B,et al. Proton NMR studies of the structural and dynamical effect of chemical modification of a single aromatic sidechain in aa snake cardiotoxin. Relation to the structure of the putative binding site and the cytolytic activity of the toxin [ J ]. J Mol Biol. 1994;243(4) :719-35. 被引量：1
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  • 10仲晓燕,刘广芬.中华眼镜蛇毒细胞毒素14的纯化及其抗癌活性[J].中国药理学报,1993,14(3):279-282. 被引量：20

二级参考文献35

  • 1仲晓燕,刘广芬.中华眼镜蛇毒细胞毒素14的纯化及其抗癌活性[J].中国药理学报,1993,14(3):279-282. 被引量：20
  • 2杨惠玲,郭禹标.蛇毒膜毒素抗肿瘤作用的研究进展[J].癌症,1996,15(1):72-73. 被引量：16
  • 3赵蓉 游云 等.蛇毒对人及小鼠传代细胞的杀伤作用[J].福建医学院学报,1988,22(3):204-204. 被引量：9
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  • 7Leung WW,Keung WM,Kong YC. The cytolic effect of cobra cardiotoxin on Ehrlich ascites tumor cells and its inhibition by Ca^2+[J]. Naunyn Schmiedebergs Arch Pharmacol, 1976,292 (2):193-198. 被引量：1
  • 8Chaim-Matyas A,Borkow G,Ovadia M. Isolation and characterization of a cytotoxin P4 from the venom of Naja Nigricollis preferentially active on tumor cells[J]. Biochem Int, 1991,24(3):415-421. 被引量：1
  • 9Fawzia M. Treatment trials of E. A. C. with crude N. nigricollis venom and its fraction Ⅱ(mice). In:Proceeding of the 7th European symposium on animal,plant and microbial toxins[M]. Prague :Carolinutn-Charles Univ Press, 1986,107-108. 被引量：1
  • 10Kumar TKS,Pandian SK,Yu C. Understanding the structure function and folding of cobra toxins[J]. Proc Natl Sci Count,1000,23(1), 1-10. 被引量：1

共引文献45

同被引文献10

  • 1丁明霞,王剑松,王婉瑜,李翀,谢蜀生,徐鸿毅.中华眼镜蛇细胞毒素体外抑制膀胱癌细胞增殖活性的实验性研究[J].昆明医学院学报,2006,27(4):6-10. 被引量：3
  • 2颜汝平,王剑松,徐鸿毅.蛇毒膜毒素抗肿瘤机制的研究进展[J].云南医药,2007,28(4):404-408. 被引量：2
  • 3Lin S R,Chang L S,Chang K L.Separation and structure function studies of Taiwan cobra cardiotoxins[J].J Protein Chem,2002,21(2):81-86. 被引量：1
  • 4Abu-Sinna G,Esmat A Y,Al-Zahaby A A,et al.Fractionation and characterization of Cerastes cerastes cerastes snake venom and the antitumor action of its lethal and non-lethal fractions[J].Toxicon,2003,42(15):207-215. 被引量：1
  • 5Suzuki K,Nakamura M,Hatanaka Y,et al.Induction of apoptotic cell death in human endothelial cells treated with snake venom:implication of intracellular reactive oxygen species and protective effects of glutathione and superoxide dismutases[J].J Biochem,1997,122(6):1260-1264. 被引量：1
  • 6Strizhkov B N,Blishchenko E Y,Satpaev D K,et al.Both neurotoxin II from venom of Naja naja oxiana and its endogenous analogue induce apoptosis in tumor cells[J].FEBS Lett,1994,340(1-2):22-24. 被引量：1
  • 7Lin M L,Lu Y C,Chung J G,et al.Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway[J].Cancer Lett,2009,291(24):46-58. 被引量：1
  • 8Trisciuoglio D,Uranchimeg B,Cardellina J H,et al.Induction of apoptosis in human cancer cells by candidaspongiolide,a novel sponge polyketide[J].J Natl Cancer Inst,2008,100(12):12331246. 被引量：1
  • 9Cura J E,Blanzaco D P,Brisson C,et al.Phase1and pharmacokineties study of crotoxin in patients with advanced cancer[J].Clin Cancer Res,2002,8(4):1033-1041. 被引量：1
  • 10雷丹青,刘绵林,蓝利,汤圣希.广西眼镜蛇蛇毒细胞毒素的抗肿瘤作用[J].实用癌症杂志,2004,19(2):127-129. 被引量：4

引证文献1

二级引证文献2

海峡药学
2007年 第11期

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