摘要
子宫内膜向蜕膜的转化是正常着床和妊娠的一个重要特征,对于胚泡着床是必不可少的。在蜕膜化过程中,子宫内膜基质细胞在形态和生理等方面都发生了很大的变化。蜕膜化过程受多种因素的调节,包括cAMP、胰岛素样生长因子结合蛋白-1(IGFBP-1)、自然杀伤细胞、同源盒基因-10(HOXA10)、激活素等。但对蜕膜化的机制及调节等仍不清楚。
The transformation of endometrium into decidua is an important feature of implantation and essential for pregnancy. During decidualization, endometrial stromal ceils have undergone large morphological and physiological changes. Decidualization is regulated by various factors, including cyclic adenosine monophosphate （cAMP）, insulin-like growth factor binding protein-1 （IGFBP-1）, natural killer （NK） cells, homeobox A 10 （HOXA 10） and heparin-binding EGF-like growth factor （HB-EGF）. However, the mechanism underlying decidualization is still unknown.
出处
《细胞生物学杂志》
CSCD
2007年第5期666-670,共5页
Chinese Journal of Cell Biology
关键词
蜕膜化
子宫内膜
基质细胞
decidualization
endometrium
stromal ceils
