摘要
目的:了解强迫症(OCD)患者免疫系统和内分泌系统的功能及两者之间的关系。方法:采用酶联免疫试验双抗体夹心法检测35例强迫症患者和30例健康者的血可溶性白细胞介素2受体(SIL-2R)及血皮质醇的含量。结果:强迫症患者血清白介素2受体基础值明显低于健康者(0.05>P>0.02),其血皮质醇的含量较健康对照组显著升高(0.005>P>0.002),强迫症患者血白介素2受体和皮质醇含量直线相关分析呈明显负相关(r=-0.856),而健康对照组无此关系。结论:强迫症患者存在免疫系统和内分泌系统的紊乱,且其免疫系统和内分泌系统间存在负相关关系。
Objective： To understand the relationship between immune system and endocrine system and their function in the patients suffered with compulsion. Methods： We use ELISA double antibody sandwich method to detect soluble IL - 2 receptor and hydrocortisone in blood serum from 35 patients and 30 healthy people. Results： The basal value of IL -2 receptor in the patients suffered with compulsion is lower than that in healthy people obviously. （0.05 〉 P 〉 0.02） , and the content of hydrocortisone increases strikingly compared to the healthy control group （0. 005 〉 P 〉 0. 002）. The straight line correlation analysis between the content of IL- 2 receptor and the hydrocortisone in the patients presents negative correlation clearly （ R = - 0. 856）. But there is no such relationship in the healthy control group. Conclusions： The disorder of immune system and endocrine system happened to the patients with compulsion and both systems have negative correlation.
出处
《中国民康医学》
2007年第17期709-710,共2页
Medical Journal of Chinese People’s Health
关键词
强迫症
受体
白细胞介素2
皮质醇
Compulsion
Interleukin - 2
Receptor
Hydrocortisone
