摘要
目的观察牡蛎肉水提液对去卵巢大鼠脑衰老的影响。方法4月龄的雌性大鼠行双侧卵巢摘除术后,给予牡蛎肉水提液灌胃3个月,测定大鼠脑形态计量学和生化指标。结果牡蛎肉水提液组大鼠的纹状皮质分子层厚度增加,分子层厚度和皮层总厚度的比值下降,海马CA2区单位面积大锥体细胞数增多,超氧化物歧化酶(SOD)活性增强而丙二醛(MDA)含量下降。结论牡蛎肉水提液能够延缓去卵巢大鼠脑衰老。
Objective To explore the effect of extract of poyster on aging of cerebra in ovariectomy rats. Methods Female SD rats aged 4 months were intragastric administrated with extract of poyster for 3 months after ovariectomized. Then morphometry and biochemical in- dicator of cerebra in rats were measured. Results Compared with others,the group whose rats were given extract of poyster had thicker mo- lecular layer of striate cortex,lower ratio between molecular layer and cortex, more giant pyramidal cells of unit area in CA2 region of hippo- campus,more activity of superoxide dismutase and less quantity of malondialdehyde. Conclusions Extract of poyster can postpone aging of cerebra in ovariectomized rats.
出处
《中国老年学杂志》
CAS
CSCD
北大核心
2007年第13期1239-1241,共3页
Chinese Journal of Gerontology
关键词
牡蛎
脑
衰老
Poyster
Cerebra
Aging
