摘要
本实验通过免疫组织化学单标及双标技术研究了大鼠下丘脑室旁核中精氨酸加压素与雌激素受体α的分布和共存。结果显示大鼠下丘脑室旁核中几乎所有的精氨酸加压素阳性细胞均呈现雌激素受体α阳性,提示ERα可能参与雌激素对下丘脑AVP神经元的神经内分泌和生理功能调节,共同参与调控动物的社会认知的巩固过程。
Immunohistochemical method was used in the present study to show the distribution and co - existence of estrogen receptor - α and arginine vasopressin in the hypothalamic paraventricular nucleus of the rat. The results showed that almost all the positive cells of arginine vasopressin - immunoreactive （IR） neurons took on the positive of estrogen receptor - α. These results suggested that estrogen receptor - α probably participated in the mediation of neuroendocrine and Physiological function of estrogen to the AVP neurons, and in the consolidation process of regulating the social recognition of the animal.
出处
《塔里木大学学报》
2007年第2期34-36,共3页
Journal of Tarim University
基金
国家自然科学基金资助项目(编号:30470537)
关键词
雌激素受体Α
下丘脑室旁核
精氨酸加压素
共表达
Estrogen receptor - α
Hypothalamic paraventricular nucleus
Arginine vasopressin
co- expression
