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海军陆战队员高温强训中注射丹参液前后血液流变学与凝血功能的变化 被引量:3

Hemorheological and coagulation system changes after salviae miltiorrhizae injection in members of marine corps under high intensity training in a hot and humid environment
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摘要 目的:观察高温高湿环境下负荷30kg野外强训时,注射丹参液前后海军陆战队员血液流变学和凝血系统的变化。方法:于2005-08在南海海面和某岛屿上选择男性解放军海军陆战队员112名,经医院全面检查身体合格,18~32岁,军龄1~14年。成建制的随机抽取55名作为训练组,负重30kg参加高温高湿环境下各种强训,另外57名陆勤人员作为对照组。训练组注射丹参液前后高温强训各8h,训练末各取1次血标本,检查两组队员凝血功能5项指标及血液流变学14项指标。结果:112名海军陆战队员均进入结果分析。①未注射丹参液前训练组全血低切黏度、全血中切黏度、全血高切黏度、血浆黏度、红细胞比积、红细胞沉降率、全血低切还原黏度、全血中切还原黏度、全血高切还原黏度、血沉方程K值、红细胞聚集指数、红细胞刚性指数、红细胞变性指数、红细胞电泳指数均高于对照组[训练组:(9.4±0.3)mPa.s,(5.6±0.4)mPa.s,(4.7±0.3)mPa.s,(1.5±0.2)mPa.s,(47.4±3.1)%,(7.3±1.1)mm/h,(19.4±3.8)mPa,s,(9.7±1.5)mPa.s,(8.0±1.5)mPa.s,(61.4±10.5),(2.7±0.2),(5.5±1.0),(0.8±0.1),(6.4±1.3);对照组:(8.1±0.5)mPa.s,(4.7±0.3)mPa.s,(4.1±0.3)mPa.s,(1.3±0.2)mPa.s,(44.8±3.3)%,(8.5±1.4)mm/h,(15.5±2.4)mPa.s,(8.2±1.5)mPa.s,(7.4±1.6)mPa.s,(51.8±9.7),(2.4±0.4),(4.5±0.8),(0.7±0.3),(5.3±1.1),P<0.05,P<0.01]。注射丹参液后训练组全血低切黏度、红细胞比积高于对照组[(8.7±0.3)mPa.s,(46.5±3.1)%;(8.1±0.5)mPa.s,(44.8±3.3)%,P<0.05]。②注射丹参液前训练组凝血酶原时间、部分活化凝血酶原时间、纤维蛋白原、D-二聚体、血清纤维蛋白降解产物、血小板与对照组相比,差异显著[训练组:(10.2±0.2)s,(23.9±1.1)s,(3.8±0.2)g/L,(309.6±13.3)mg/L,(7.7±0.4)mg/L,(270.1±14.2)×109L-1;对照组:(11.6±0.3)s,(28.4±1.4)s,(2.9±0.4)g/L,(241.5±13.7)mg/L,(5.9±1.2)mg/L,(174.5±22.0)×109L-1,P<0.01]。注射丹参液后训练组血小板、D-二聚体、纤维� AIM: To observe the alterations of hemorheology and coagulation system after injecting salviae miltiorrhizae in members of marine corps under high-strength military training with 30 kg loads in a hot and humid environment. METHODS: 112 male members of marine corps aged 18-32 years with the enrollment years of 1-14, who were checked up in a good condition, were selected from the South maritime space and some island in August 2005. Fifty-five members were randomly selected as training group to participate the training with 30 kg loads in a hot and humid environment; the rest 57 members served as control. The training group carried out the intensity training for 8 hours before and after injected salviae miltiorrhizae and blood was taken at the end of training distinctly to detect the 5 cruor indexes and 14 hemorheological indexes. RESULTS: All 112 members were involved in the result analysis. (1)Before salviae miltiorrhizae injection, the hemorheological indexes of the training group were higher than the control group such as whole blood low shearing viscosity, whole blood middle shearing viscosity, whole blood high shearing viscosity, plasma viscosity, packed cell volume, erythrocyte sedimentation rate, whole blood low shearing reduction viscosity, whole blood middle shearing reduction viscosity, whole blood high shearing reduction viscosity, sedimentation equation K value, erythrocyte aggregation exponent, erythrocyte rigidity exponent, erythrocyte degeneration exponent and erythrocyte electrophoresis exponent [training group: (9.4±0.3) mPa·s, (5.6±0.4) mPa·s, (4.7±0.3) mPa·s, (1.5±0.2) mPa·s, (47.4±3.1)%, (7.3±1.1) mm per hour, (19.4±3.8) mPa·s, (9.7±1.5) mPa·s, (8.0±1.5) mPa·s, (61.4±10.5), (2.7±0.2), (5.5±1.0), (0.8±0.1), (6.4±1.3); control group: (8.1±1.5) mPa·s, (4.7±0.3) mPa·s, (4.1±0.3) mPa·s, (1.3±0.2) mPa·s, (44.8±3.3)%, (8.5±1.4) mm per hour, (15.5±2.4) mPa·s, (8.2±1.5)
出处 《中国组织工程研究与临床康复》 CAS CSCD 北大核心 2007年第30期6026-6027,6031,共3页 Journal of Clinical Rehabilitative Tissue Engineering Research
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