摘要
目的:探讨全身18氟[18F]-FDGPET/CT在原发灶不明的淋巴结转移癌中的应用价值.方法:原发灶不明的淋巴结转移癌患者56例行全身18F-FDGPET/CT检查,分别对单独PET图像、单独CT图像及PET/CT融合图像进行判读,所得结果与病理和/或随访结论比较.结果:PET/CT对原发灶检出率优于单独PET及单独CT(检出率分别为58.9%(33/56),44.6%(25/56),及35.7%(20/56),均有统计学差异(P<0.01).30.4%患者(17/56)经PET/CT检查后发现分期改变(含6例未找到原发灶患者).PET/CT,单独PET及单独CT假阳性率分别为5.4%(3/56)、16.1%(9/56)及7.1%(4/56).结论:18F-FDGPET/CT全身显像对于寻找原发灶不明的淋巴结转移癌患者的原发灶及全身侵犯情况有重要的临床价值.
AIM： To retrospectively evaluate the role of whole body ^18F-FDG PET/CT in depicting the primary lesion and in evaluating the extent of tumor invasion in cervical metastatic carcinoma of unknown primary site （LCUP）. METHODS： Fifty-six LCUP patients was included and underwent whole body ^18F-FDG PET/CT imaging to search the primary lesion. A radiologist and a nuclear medicine specialist performed blinded interpretation of PET alone, CT alone and dual-modality PET/CT imaging. RESULTS： The detection efficacy of dual-modality PET/CT （58.9%, 33/56） was higher than that of PET alone （44.6%, 25/56） and CT alone （35.7%, 25/56） with statically significant differences （χ^2 =31.48, 21.68, P 〈0.01）. The staging evaluation of 17 patients （30.4%, 17/56） was changed after whole body ^18F-FDG PET/CT imaging （including 6 patients with no primary lesion found ）. The false positive rates （FPR） of dualmodality PET/CT, PET alone and CT alone were 5.4% （3/56） , 16.1% （9/56） and 7. 1% （4/56） respectively. CONCLUSION： Whole body ^18F-FDG PET/CT may be of relatively higher value in identifying the primary tumor of LCUP patients and in displaying the extent of tumor invasion.
出处
《第四军医大学学报》
北大核心
2007年第13期1193-1195,共3页
Journal of the Fourth Military Medical University
关键词
癌/继发性
原发灶
体层摄影术
x线计算机
脱氧葡萄糖
carcinoma/SC
primary lesion
tomography, emission-computed
tomography, X-ray computed
deoxyglucose
