摘要
目的探讨18F-FDG PET/CT在查找骨转移瘤原发灶中的应用价值及不同类型骨转移瘤的PET/CT特点。方法回顾性分析34例原发灶不明的骨转移瘤患者病例资料,经常规检查未发现原发灶,行18F-FDG PET/CT扫描查找原发灶。比较溶骨性转移瘤和成骨性转移瘤SUVmax的差异。结果经组织细胞学或3个月以上的临床随访证实,34例患者中,PET/CT检出22例原发灶(64.71%)。12例PET/CT未发现原发灶(35.29%)。23例溶骨性为主转移瘤和11例成骨性为主转移瘤的SUVmax分别为6.78±3.66和4.13±1.69(P<0.05)。结论18F-FDG PET/CT显像可提示多数骨转移瘤患者的原发灶,进而指导患者的治疗计划。溶骨性转移瘤的代谢活性较成骨性转移瘤更高。
Objective To assess the value of 18F-FDG PET/CT in detecting primary tumors of patients with bone metastases,and to observe PET/CT characteristics of different types of bone metastases.Methods Whole-body 18F-FDG PET/CT images of 34 patients with metastatic bone from unknown primary tumor（CUP） were retrospectively analyzed,and SUVmax was compared in osteolytic and osteoblastic subgroups based on CT characteristics.Results Diagnosis of these patients were confirmed by histopathological findings or ≥3 months follow-up.Primary tumors were detected with PET/CT in 22 patients（64.71%）.SUVmax was 6.78±3.66 in 23 osteolytic metastases,and 4.13±1.69 in 11 osteoblastic metastases（P〈0.05）.Conclusion 18F-FDG PET/CT is helpful to find the localization of unknown primary tumors in patients with bone metastases,and to make treatment Planning.Osteolytic metastases show higher metabolic activity on 18F-FDG PET/CT.
出处
《中国医学影像技术》
CSCD
北大核心
2009年第12期2275-2278,共4页
Chinese Journal of Medical Imaging Technology
