摘要
目的研究早产儿视网膜病（retinopathy of prematurity，ROP）的发生率、高危因素、治疗及预后。方法对2002年8月至2003年2月间收住北京妇产医院新生儿重症监护病房胎龄≤35周且出生体重≤2500g的74例早产儿于生后35周进行眼底检查，诊断ROP者2～3周随访一次，ROP病变发展到阈值及以上者手术治疗，其中56例早产儿于2～3岁时行眼瞬息图象筛分仪筛查视功能。结果检出ROP患儿11例，包括Ⅰ期4例，Ⅱ期4例，Ⅲ期3例，发生率为14．9％。其中Ⅰ、Ⅱ期病变均恢复正常；3例Ⅲ期阈值患儿给予手术治疗。ROP高危因素分别为早产、低出生体重和氧疗。56例早产儿在2～3岁时发现屈光不正26例，斜视8例，白内障1例。结论ROP在早产儿发生率较高，程度较重，对患儿远期视功能影响较大。建议对早产儿尤其是有高危因素的早产儿于生后4周左右常规进行眼科检查，并定期随访，以早发现、早治疗，改善ROP患儿预后，提高生命质量。
Objective To investigate the incidence and the prognosis of premature infants with retinopathy of prematurity（ROP） ,and analyze its risk factors. Methods Seventy-four premature infants with gestational age no more than 35 weeks and birth weight no more than 2500 g hospitalized in our care unit from Aug. 2002 to Feb. 2003 were enrolled in this study. Regular eye examinations were performed on all subjects and visual function was followed up with medical technology and innovations. Results Eleven premature infants were diagnosed as ROP with the incidence 14.9%,including 4 infants with stage 1,4 with stage Ⅱ and 3 with stage Ⅲ. The infants with stage Ⅰ or Ⅱ ROP recovered naturally. Three infants with stage Ⅲ ROP received laser therapy. The high risk factors of ROP were premature delivery,low birth weight and long-term oxygen therapy. Fifty-six premature infants were followed-up till they were 2 to 3 years old. Twenty-six children suffered from refractive error, 8 children with strabismus and 1 child with cataract. Candusions All premature infants with high risk factors are suggested to have regular ophthalmic examination, and follow-up to focus on their visual function.
出处
《中华围产医学杂志》
CAS
2007年第3期179-182,共4页
Chinese Journal of Perinatal Medicine
关键词
视网膜病
早产儿
危险因素
随访研究
Retinopathy of prematurity
Risk factors
Follow ups studies
