摘要
目的 多中心调查国内早产儿视网膜病（retinopathy of prematurity，ROP）发病情况，建立ROP筛查制度。方法 建立由11家医院参加的多中心筛查协作网，对2005年1月1日至12月31日在合作单位出生或收治的出生体重＜2000g的低出生体重儿进行ROP筛查。结果 在完成随访的621例研究对象中73例发生ROP，发病率为11．8％；出生体重在1500-1999g者25例发生ROP，发生率为5．9％；出生体重在1000-1499g者45例发生ROP，发生率为23．6％；出生体重〈1000g者3例发生ROP，发生率为60．0％。发生1期ROP24例，2期ROP35例，3期及以上ROP14例；激光治疗16例，冷冻术8例，玻璃体切除术1例，无失明病例。结论 出生体重〈2000g的早产儿ROP发生率为11．8％，筛查能使ROP得到早期诊断和治疗，降低ROP的危害，可在全国范围推广。
Objective The aim of present study is to evaluate the ROP situation in China, and to investigate the incidence of ROP by a prospective multicenter study. Methods Eleven children＇s hospitals and maternal hospitals were selected to form a multicenter network. All infants with birth weight〈2000 g born in or transferred to one of the participating centers from 1 January to 31 December 2005. were enrolled in this study. Ophthalmologic examinations of each infant were performed on time by skilled ophthalmologists. Results Six hundreds and twenty-one infants finished the followup. It was found that 73 out of 621 infants had ROP（11. 8%）. Among which 5.9% of infants with birth weight between 1500 g and 1999 g, 23.6% with birth weight between 1000 and 1499 g, and 60.0% with birth weight 〈1000 g had ROP. Twenty-four infants had stage Ⅰ ROP,35 infants had stage Ⅱ ROP,and 14 infants had stage Ⅲ or more severe ROP. Sixteen infants received laser therapy, 8 infants had cryotherapy, and 1 infant had vitrectomy. Conclusions The ROP screening may contribute to early diagnosis and early treatment, which could reduce the damage due to ROP. Standard ROP screening system should be carried on all over the country.
出处
《中华围产医学杂志》
CAS
2006年第6期369-372,共4页
Chinese Journal of Perinatal Medicine
关键词
视网膜病
早产儿
发病率
多中心研究
Retinopathy of prematurity
Incidence
Risk fators
Multicenter studies
