摘要
目的:了解汕头地区早产儿视网膜病变(retinopathy of prematurity,ROP)发病情况,探讨适合汕头地区的ROP筛查标准。方法:对2011-01/2014-12在汕头4家医院NICU住院的1 813例出生体重≤2 000g的低出生体重儿或胎龄≤34周的早产儿采用双目间接眼底镜和(或)广角数码儿童成像系统(Ret CamⅡ)进行ROP筛查,所有患儿随访至视网膜完全血管化或病变退化。结果:发现ROP 202例388眼,占筛查总例数11.14%。其中重症ROP(阈值前期Ⅰ型或阈值期)43例85眼,占筛查总例数2.37%。出生体重<1 500g新生儿408例,重症ROP 34例67眼,占全部重症ROP病例的79.07%。GEE模型分析结果表明,低出生体重、小胎龄及吸氧是ROP的高危因素。结论:汕头地区ROP检出率11.14%,但重症ROP检出率较低,主要发生于出生体重<1500g低出生体重儿和出生胎龄≤34周的早产儿。低出生体重、小胎龄及吸氧是ROP的高危因素。
AIM：To determine the incidence of retinopathy of prematurity（ROP） and to investigate the appropriate criteria for the screening ROP in Shantou.METHODS：A total of 1 813 infants with birth weight ≤2000g or gestational age ≤34wk in neonatal intensive care units（NICU） of four hospitals in Shantou were screened with binocular indirect ophthalmoscope and（or） wild-field digital pediatric retinal imaging system（RetCam Ⅱ）from January 2011 to December 2014.All infants were followed up until the retina was completely vascularized or until the disease regressed.RESULTS：In all infants,ROP was detected in 388 eyes of202 cases（11.14%）,including 85 eyes of 43 cases（2.37%） suffering from severe ROP（threshold or pre-threshold type Ⅰ ROP）.34 severe cases（67 eyes） were screened out in 408 infants with birth weight 〈1 500 g,accounted for 79.07%in all severe cases.GEE model analysis indicated that low birth weight,small gestational age and oxygen therapy were high risk factors of ROP.CONCLUSION：The detection rate of ROP is 11.14%in Shantou NICU.However,the detection rate of severe ROP is lower,mainly in the infants with birth weight 1 500 g and gestational age ≤ 34wk;Low birth weight,small gestational age and oxygen therapy are high risk factors of ROP.
出处
《国际眼科杂志》
CAS
2015年第8期1455-1457,共3页
International Eye Science
