摘要
研究11种菌株对喜树碱的生物转化作用。结果表明,毛霉和禾谷镰刀菌对喜树碱具有生物转化能力;采用玉米粉培养基为转化培养基,毛霉对喜树碱的最佳转化条件为温度30℃,时间96 h,转化浓度150μg/mL,转化初始pH为6。
Eleven strains was studied for the transformation of Camptothecin in this paper. The results showed that Camptothecin can be transformed by Mucor mucedo and Fusariurn grarninearurn. The optimum conditions for the of by when Mucor rnucedo was incubated in the corn meal medium at 30 ℃ and, initial pH 6 for 96 h the maximum Camptothecin transformation was obtained, in which the of Camptothecin concentration is 150μg/mL.
出处
《大连轻工业学院学报》
2007年第1期18-20,共3页
Journal of Dalian Institute of Light Industry
关键词
喜树碱
微生物转化
菌株筛选
Camptothecin
microbial transformation
microbial strain screening
