摘要
二甲基亚砜(DMSO)作为一种溶解性能良好的溶剂被广泛用于微生物转化,对多数微生物均具有很好的相容性。考察了DMSO对16种自有毛霉的生长代谢的影响。薄层色谱显示,加入DMSO后,10#菌株可产生多种新的代谢产物,且这些代谢产物是逐渐产生并累积的。研究表明,DMSO对10#毛霉的生长代谢有明显影响,从而有可能改变该菌株的其它性能,如生物催化性、遗传稳定性等。
As a solvent with good solubility, dimethyl sulfoxide （DMSO） is commonly used in the micro bio- transformation,which has the desirable compatibility to most mircrobes. In this paper,the effects of DMSO on metabolism of sixteen kinds of self-owned mucor were explored and it was found that DMSO had a great effect on the secondary metabolites of mucor 10a. The results of thin-layer chromatography showed that with DMSO adding,mucor 10# metabolized several products which did not exist in the control group without DMSO,and these metabolites generated gradually and accumulated. The research indicated that DMSO could affect growth and metabolism of mucor 10#,and may thereby change its other characteristics such as biocatalytie property, hereditary stability, etc.
出处
《化学与生物工程》
CAS
2013年第5期49-50,共2页
Chemistry & Bioengineering
基金
天津科技大学实验室开放基金资助项目(1104A209)
天津科技大学科学研究基金资助项目(20120116)
