摘要
目的分析耐甲氧西林金黄色葡萄球菌(MRSA)和耐甲氧西林表皮葡萄球菌(MRSE)医院感染的危险因素,防止感染暴发和流行。方法采用前瞻性监测方法,对58 422例住院患者发生的MRSA、MRSE医院感染病例进行调查分析。结果我院两年内共发生MRSA、MRSE医院感染173例;年龄≥60岁118例,感染前使用≥3种抗菌药物114例,有侵入性操作100例,有≥3种严重基础疾病62例;感染部位为呼吸道105例,分布在ICU 59例。结论MRSA、MRSE医院感染的危险因素主要是高龄、住院时间过长、不规范使用抗菌药物、侵入性操作、严重的基础疾病等;高发科室为ICU、神经科和器官移植科;高发部位是呼吸道。
OBJECTIVE To analyze the predisposing factors in nosoeomial infections of metieillin-resistant Staphylococcus aureus （MRSA） and metieillin-resistant S. epidermidis （MRSE）, and to prevent their spread and prevalence. METHODS The predisposing factors were analyzed in 173 eases of MRSA and MRSE infections that were registered prospectively between Jan 2001 and Dee 2002. RESULTS One hundred and eighteen eases with age ≥60 were administrated with three combined antibiotics. One hundred eases received invasive operations. Sixty two eases were with serious multi-systemic （〉3 systems） underlying diseases. One hundred and five eases with respiratory tract infections ranked on top of distribution of infected tissues, 59 eases happened in ICU wards. CONCLUSIONS The predisposing factors of hospital infections are aging, long hospitalization, inappropriate use of antibiotics, invasive operations and serious underlying diseases. Hospital infections happen highly in ICU, department of neurology, and organ transplantation departments. The most infected site is respiratory tract.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2007年第4期465-467,共3页
Chinese Journal of Nosocomiology
