摘要
肠抑胃肽又称葡萄糖依赖性胰岛素释放多肽（GIP），是一种重要的肠促胰岛素，其受体除分布在胰腺B细胞外，还分布于胃、小肠、脂肪组织、肾上腺皮质、垂体、骨以及脑组织的一些区域等。研究GIP在这些组织及相关疾病，如营养过剩诱导的肥胖症、食物依赖的库欣综合征中的作用可能会为临床上一些常见病和罕见病的治疗带来新的希望。
Gastric inhibitory peptide or glucose-dependent insulinotropic polypeptide（GIP） is an important incretin. In addition to β cells, GIP receptor is also expressed in various tissues including stomach, small intestine, adipose tissue, adrenal cortex, pituitary body, bone, vascular endothelial cells and brain. The study of effects of GIP on these tissues and correlated diseases such as ovemutrition-induced obesity, food-dependent Cushing＇s syndrome, may bring new hope for the treatment of some common and rare diseases.
出处
《国际内分泌代谢杂志》
2007年第2期92-94,共3页
International Journal of Endocrinology and Metabolism
