摘要
目的研究注射用马来酸桂哌齐特在5%葡萄糖、10%葡萄糖、氯化钠、葡萄糖氯化钠输液中配伍稳定性。方法建立注射用马来酸桂哌齐特在四种输液中的紫外分光光度法含量测定方法,分析混合液在25℃、37℃条件下6 h内药物含量,并观察其外观、pH值及紫外光谱。结果6 h内混合液外观、pH值及紫外光谱无明显变化。结论在25℃、37℃条件下,注射用马来酸桂哌齐特与四种输液配伍后6 h内稳定性较好。
Aim To study the compatible stability between einepazide maleate injection and four injections （5% GS, 10% GS, NS and GNS）. Methods The UV method for determining einepazide maleate injection and four injections in their mixed solutions were established ,by which they were assayed when the mixed solution was set at 25℃and 37℃ within 6 h. The appearanee,pH values and UV spectrum of the mixed solutions were also examined. Results The appearance ,pH values and UV spectrum of the mixed solutions didn＇ t change obviously within 6 h. Conclusion They were stable when einepazide maleate injection was mixed with any of the four injections within 6 h.
出处
《安徽医药》
CAS
2007年第3期259-260,共2页
Anhui Medical and Pharmaceutical Journal
关键词
马来酸桂哌齐特
输液
配伍稳定性
einepazide maleate injection
injections
compatible stability
