摘要
目的研究中药胆木水溶性部位的化学成分。方法采用大孔吸附树脂,硅胶柱色谱和Sephadex LH20凝胶柱色谱分离纯化,通过光谱分析鉴定化合物的结构。结果从胆木水溶性部位中分离得到7个化合物,分别鉴定为:nauc leam ide A-10-O--βD-glucopyranoside(I),5--βcarboxystrictosid in(II),獐牙菜苷(III),番木鳖苷A(IV),3,4-d im ethoxyphenyl--βD-glucopyranoside(V),3,4,5-trim ethoxyphenyl--βD-glucopyranoside(V I),2-phenethylrutinoside(V II)。结论化合物I为新的吲哚类生物碱苷,化合物I^V II均为首次从该植物中分得。
Aim To investigate the chemical constituents of water-soluble part of stem of Nauclea officinalis. Methods The compounds were isolated and purified by resins, silica gel, and Sephadex LH20 column chromatography repeatedly, and their structures were identified by spectral analysis. Results Seven compounds were isolated and identified as： naucleamide A-10-O-β-D-glucopyranoside （Ⅰ）, 5-β- carboxystrictosidin （Ⅱ）, sweroside （Ⅲ）, loganin （Ⅳ）, 3,4-dimethoxyphenyl-β-D-glucopyranoside （Ⅴ）, 3,4, 5-trimethoxyphenyl-β-D-glucopyranoside （ Ⅵ ） , 2-phenethylrutinoside （ Ⅶ ）. Conclusion Compound Ⅰ is a new indole alkaloid glucoside, compounds Ⅰ -Ⅶ were isolated from this plant for the first time.
出处
《药学学报》
CAS
CSCD
北大核心
2006年第11期1064-1067,共4页
Acta Pharmaceutica Sinica
