摘要
合成了川芎嗪体内主要代谢产物2-羟甲基-3,5,6-三甲基吡嗪.以川芎嗪为阳性对照观察了它对血液流变性的影响。
2 Hydroxymethyl 3,5,6 trimethyl pyrazine was synthesized.It is the essential intracorporal metabolite of tetramethyl pyrazine.Tetramethyl pyrazine was taken for positive control and compared among them on its rheologic parameters.It was found that both drugs showed no significant difference.
出处
《中国药物化学杂志》
CAS
CSCD
1996年第4期254-256,共3页
Chinese Journal of Medicinal Chemistry
关键词
川芎嗪
羟甲基
三甲基吡嗪
血液流变性
Tetramethyl pyrazine
2 Hydroxymethyl 3,5,6 trimethyl pyrazine
Rheologic parameters