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共聚物水凝胶角膜接触镜材料的离子渗透性研究 被引量:3

Synthesis of Copolymer Hydrogel for Cornea Contact Lens and Study on Its Ion Penetration Capability
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摘要 以偶氮二异丁腈(AIBN)为引发剂,N-乙烯吡咯烷酮(NVP)单体、甲基丙烯酸-β-羟乙酯(HEMA)单体、γ-(甲基丙烯酰氧)丙基三甲氧基硅烷(KH570)单体及交联剂N,N'-亚甲基双丙烯酰胺(Bis)在一定温度下共聚制得软性角膜接触镜材料--水凝胶,并采用池膜测量法研究了钠离子在角膜接触镜材料中的渗透性能。实验发现,随NVP含量的增大,水凝胶的含水量增大,钠离子渗透性能增强;KH570含量小于15%时,钠离子渗透性能随KH570含量的增加而增强,而含量在15%~25%时钠离子渗透性能则降低;交联剂含量增大会降低钠离子的渗透性能,含量以不超过0.7%为宜。 The hydrogel used as the material of soften cornea contact lens is synthesized by copolymerization, It adopt N-vinylpyrrolidone (NVP), methacrylic acid-β-hydroxyethl methacrylate (HEMA) and KH570 as monomers, with Bis as crosslinker and azobis iso butyro nitrile(AIBN) as initiator. Cavity-membrane measuring method is adopted to study the sodium penetration capability, It is found that the penetration capability increases with the increase of NVP in the copolymer hydrogel. The sodium penetration capability increases with the increase of KH570 less than 15%. However, 15% - 25 % content of KH570 would decrease penetration capability. The increase of crosslinker content would also decrease the sodium penetration capability when its content is not more than 0. 7%.
出处 《材料导报》 EI CAS CSCD 北大核心 2006年第12期134-136,共3页 Materials Reports
基金 国家自然科学基金资助项目(No.29976007) 广东省自然科学基金资助项目(No.5300978)
关键词 N-乙烯吡咯烷酮 水凝胶 角膜接触镜 离子渗透性 N-vinylpyrrolidone(NVP), hydrogel, cornea contact lens, ion penetration capability
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参考文献10

  • 1Peppas N A.Hydrogels in medicine and pharmacy[M].Boca Raton:CRC Press Inc,1986 被引量:1
  • 2Franklin V J,Bright A M,Tighe B J.Hydrogel polymers and ocular spoilation process[J].Trends Polym Sci,1993,1:9 被引量:1
  • 3Compan V,Lopez M L,et al.Determination of the oxygen transmissibility and permeability of hydrogel contact lens[J].J Appl Polym Sci,1999,(2):321 被引量:1
  • 4Compan V,Guzman J,Riande E.A potentiostatic study of oxygen transmissibility and permeability through hydrogel membranes[J].Biomaterials,1998,19:2139 被引量:1
  • 5Griesser H J,Laycock B G.Extended wear ophthalmic lens[P].WO 9631792.1996-10-10 被引量:1
  • 6贾绍义,柴诚敬主编..化工传质与分离过程[M].北京:化学工业出版社,2001:482.
  • 7韩慧芳..有机硅改性PVP水凝胶软接触透镜材料的合成与性能研究[D].广东工业大学,2004:
  • 8谭帼馨,崔英德.NVP-HEMA角膜接触镜材料的透氧性能[J].膜科学与技术,2004,24(2):26-29. 被引量:8
  • 9黎新明..共聚物水凝胶接触镜材料的制备与性能研究[D].西北工业大学,2003:
  • 10郑荣领,周电根,郑一仁.角膜接触镜研究进展[J].中国实用眼科杂志,2000,18(5):262-265. 被引量:7

二级参考文献13

  • 1Payor R E,CLAO J,1995年,21卷,163页 被引量:1
  • 2Young G,CLAO J,1997年,23卷,226页 被引量:1
  • 3Lai Y C,J Biomed Mater Res,1997年,35卷,349页 被引量:1
  • 4Fonn D,Situ P,Simpson T. Hydrogel lens dehydration and subjective comfort and dryness ratings in symptomatic and asymptomatic contact lens wearers[J]. Optometry and Vision Sci, 1999,76(10): 700- 704. 被引量:1
  • 5Mirejovsky D, Archana S. Water properties of hydrogel contact lens materials: a possible predictive model for corneal desiccation staining[J]. Biomaterials, 1993, 14(14):1080-1087. 被引量:1
  • 6Compan V, Guzman J, Riamde E. A potentiostatic study of oxygen tramsmissibility and permeability through hydrogel membranes[J]. Biomaterials, 1998,19(23): 2139- 2145. 被引量:1
  • 7Hirata Y, Miura Y, Tanaka S. Synthesis and hydration properties of copolymers having sugar side chains and their oxygen permeability in the wet state[J]. J Membr Sci,2000,176: 21-30. 被引量:1
  • 8陆学红 程行 孙以实.共聚水凝胶溶涨特性的研究[J].高分子学报,1987,1(1):69-74. 被引量:1
  • 9谢培英.角膜接触镜[M],第2版[M].北京:人民卫生出版社,1998.243-263. 被引量:1
  • 10温建业,孙以实.N-乙烯基吡咯烷酮-甲基丙烯酸β羟乙酯共聚反应研究[J].高分子材料科学与工程,1989,5(1):20-26. 被引量:4

共引文献12

同被引文献32

  • 1姚子昂,吴海歌,韩宝芹,刘万顺.壳聚糖—透明质酸共混膜性质的研究[J].高技术通讯,2004,14(9):95-99. 被引量:12
  • 2黎新明,崔英德,尹国强,贾振宇,廖列文.单体组成对水凝胶接触镜材料结构的影响[J].化工新型材料,2005,33(7):22-23. 被引量:1
  • 3刘祖国,张慧.重视我国角膜病的基础研究[J].中华眼科杂志,2006,42(8):673-675. 被引量:22
  • 4何曼君,张红东,陈维孝,等.高分子物理(第三版)[M].上海:复旦大学出版社,2008. 被引量:3
  • 5Iguchi M, Yamanaka S, Budhiono A. Bacterial cellu- lose-a masterpiece of nature's arts[J. Journal of Ma- terials Science, 2000,35 : 161-270. 被引量:1
  • 6Czaja W K, Young D J, Kawecki M, et al. The future prospects of microbial cellulose in biomedical applica- tions[J]. Biomacromolecules, 2007, 8 : 1-12. 被引量:1
  • 7Serafica G, Weinberger L.Porous structures of microbial- derived cellulose for in bivo implantation[-P.US: A1, 20100158985, 2010-7-24. 被引量:1
  • 8Lima G, Sierakowski M R, Faria-Tiseher P C S, et al. Characterisation of bacterial cellulose partly acetylated by dimethylacetamide/lithium chloride [J]. Mater Sci Eng C, 2011, 31(2) :190-197. 被引量:1
  • 9Kadokawa J, Murakami M, Kaneko Y. A facile prepara- tion of gel materials from a solution of cellulose in ionic liquid[J.Carbohydrate Research, 2008,343 : 769-772. 被引量:1
  • 10Yang Q L, Qi H S, Lue A, et al. Role of sodium zincate on cellulose dissolution in NaOH/urea aqueous solution at low temperature[J. Carbohydr Polym, 2011, 83: 1185-1191. 被引量:1

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