摘要
茄尼醇有较强的抗癌生物活性,能够抗菌消炎,是合成心血管疾病、抗癌、抗溃疡等新型药物的中间体,概括了茄尼醇的国内外应用情况,并对其衍生物辅酶Q10、N-茄呢基谷氨酰胺类化合物、N-酰基-N′-茄呢基哌嗪衍生物、二元酸茄呢醇乙酰葡萄糖二酯的合成路线及在医学领域应用进行总结,为茄尼醇衍生物的合成研究提供依据。
Solanesol has antiseptic and anticancer activity. It is used as synthesis intermediate of new drugs for treating cardiovascular disease or for use as anticancer, antiulcer and so on. Applications and synthesize paths of its derivants such as Q10, N-solancsylglutamide derivatives, N-acyl-N-solanesylpiperazine derivatives and solancsyl glucosyl dibasic acid esters were summarized.
出处
《化学世界》
CAS
CSCD
北大核心
2006年第11期692-695,共4页
Chemical World
关键词
茄尼醇
应用
衍生物合成
solanesol
application
synthesis of derivant
