摘要
血小板活化因子（ＰＡＦ）作为受体的介质而与炎症、过敏等多种生理过程有关。作者介绍一种简易的血小板聚集玻片法用以从药用植物中初筛抗ＰＡＦ活性成分，并合成了Ｌ—６５２，７３１且以其作为标准拮抗剂。
In order to screening the anti-PAF constituents from medicinal plants,a simple smear method was used to observe the aggregation of blood platelets induced by PAF under microscrope. The results were divided into four grades with L-652,731 as a standard antagonist.This method was compared with Born's turbidimetric method and applied in screening different fractions isolated from Fritillaria Ussuriensis。
出处
《上海第二医科大学学报》
CSCD
1996年第5期315-317,共3页
Acta Universitatis Medicinalis Secondae Shanghai
基金
国家自然科学基金
关键词
血小板活化因子
筛选法
L-652
731
拮抗剂
platelet activating factor
anti-PAF constituents
screening method
L-652,731antagonist
