摘要
目的反流性食管炎24 h pH监测症状指数的临床应用价值。方法内镜下确诊为反流性食管炎100例,在3 d内进行24 h食管内pH监测,采用Ward建立的数学表达式"症状指数"(symptom index,SI)分别分析烧心、胸痛的症状指数。结果经24 h pH监测所测得烧心SI,异常组SI百分率增高呈阶梯样上升,正常组随SI百分率增高呈阶梯样下降。异常组与正常组相比较,低SI≤25.0%无差异(P>0.05),而高SI≥50.0%,SI≥75.0%差异有显著性(P<0.01)。烧心轻、中、重程度也与SI百分率增高呈正相关性。烧心与酸反流的定量参数有相当密切的联系。高SI≥50.0%与SI≥75.0%无差异(P>0.05),将50%定为症状指数为妥。胸痛SI与酸反流关系不密切。结论 SI≥50%与24 h食管内pH监测结果有互补性,是制定治疗方案的依据。
AIMS To study the clinical significance of reflux esophagitis symptom index(SI). METHODS To correlate SI (pH<4) with heart burn, chest pain and acid reflux, we measured the 24 hour pH of esophagus of 100 patients with refluxes esophagitis by using digitrapper MK-111. RESULTS In abnormal group, heart burn increased like step shape When SI percentage rose, with remarkable difference between lower SI(>25.0%) and higher SI(≥50,0% and≥75.0% )(P<0.01). The SI was strongly associated with the lower, middle and higher heart burn and with the fixed quantity parameter of acid reflux. CONCLUSIONS SI≥50.0% is a clinical basis for treatment.
关键词
食管炎
反流性食管炎
症状指数
esophagitis
gastroesophageal reflux hydrogension concentration
chest pain
