摘要
应用自制的仪器作持续２４小时食管ｐＨ监测，并作食管测压、钡餐造影、内镜及粘膜活检等多种检查，对２０例伴胃—食管反流症状的患者进行了研究。另对２０例无症状的正常志愿者进行了持续ｐＨ监测和食管测压检查作对照。自制的监测仪器性能良好而稳定。病例组中持续ｐＨ监测各反流参数、下食管括约肌压力及原发性蠕动收缩波幅与正常对照组比较，差异有非常显著性（Ｐ＜０．００１），而二组之下食管括约肌长度间，差异无显著性（Ｐ＞０．０５）。本研究建立２４小时ｐＨ监测及下食管括约肌压力的正常值范围，还比较了上述各检查方法对胃—食管反流的阳性检出率，以持续ｐＨ监测最高（９０％），提示ｐＨ监测的诊断价值极高。
mbulatory 24-hour esophageal pH
monitoring,esophageal manometry,esophagram,esophagoscopy,and mucosal biopsy were
performed in 20 patiente with gastroesophagealreflux symptoms.Additionally,20 asymptomatic
healthy volunteers underwent pH monitoringand esophageal manomety.In the patients with
reflux symptoms,all reflux variables,loweresophageal sphincter pressure,and primary
peristaltic contraction amplitude were signifi- cantly different from those of normal
subjects(P<0.001),length was not significantlydifferent(P>0.5)from that of normal subjects.We
establish optimal thresholds of 24-hour pH- metry and lower esophageal sphincter
pressure.Prolonged pH monitoring was found to havethe best sensitivity(90%)of any
above-mentioned clinical test of gastroesphageal reflux.It issuggested that sustained pH
monitoring is of very important value for diagnosis ofgastroesophageal reflux.
出处
《中华消化杂志》
CAS
CSCD
北大核心
1994年第3期143-146,共4页
Chinese Journal of Digestion
关键词
监测
pH监测系统
反流性食管炎
Prolonged pH monitoring
Gastroesophageal reflux
Lower esophageal sphyncter pressure.
