摘要
目的:调查临床结核菌分离株对链霉素的依赖状况。方法:采用双向匡氏琼脂培养基分离痰结核菌和作结核菌依赖性测定,采用匡氏琼脂培养基检测结核菌耐药性。结果:184例临床分离结核菌株链霉素的依赖情况:含药管结核菌的生长较对照管明显粗大旺盛,且高浓度管菌落数≥低浓度管者占11.41%(21/184);含药管结核菌的生长较对照管明显粗大旺盛,且低浓度管菌落数>高浓度管者占2.72%(5/184);低浓度管结核菌的生长较对照管明显粗大旺盛,而高浓度管菌落数<对照管者占4.35%(8/184);高浓度管结核菌的生长较对照管明显粗大旺盛,而低浓度管菌落数<对照管者占4.35%(8/184)。总计,显示链霉素依赖特征的临床分离株占22.83%(42/184)。结论:约22.8%的结核菌临床分离株显示出链霉素依赖性,并具有不同的依赖特征。
Objective： To investigate the streptomycin-depending of clinical isolated strains of M. tuberculosis. Methods ：The isolation and drug-depending of tuberculosis were done by double-phase Kuang＇s agar medium, and the drug-resistance of tuberculosis were carried by Kuang＇s agar medium. Results ：The condition of depending streptomycin in 184 clinical isolates of M. tuberculosis were as follows ： The strains which grew faster and more vigorous in the drug tubes than those in the contrast tubes, and the growth in high concentration tubes ≥those in low concentration tubes covered 11.41% （21/184） ;The strains which grew faster and more vigorous in the drug tubes than those in the contrast tubes, and the growth in low concentration tubes 〉 those in high concentration tubes covered 2.72% （5/184） ;The strains which grew faster and more vigorous in low concentration tubes than those in the contrast tubes, and the growth in high concentration tubes 〈 those in the contrast tubes covered 4.35 % （8/184） ;The strains which grew faster and more vigorous in high concentration tubes than in the contrast tubes, and the growth in low concentration tubes 〈 those in the contrast tubes covered 4.35% （ 8/184 ） ; In brief, the streptomycin-depending strains among clinical isolates covered 22.83% （42/184）. Conclusion ：There were streptomycin-depending strains in the clinical isolates of tuberculosis, and different depending features were existed among those strains.
出处
《军医进修学院学报》
CAS
北大核心
2006年第3期212-213,共2页
Academic Journal of Pla Postgraduate Medical School
