摘要
本文于Ｂｒｉｔｔｏｎ－Ｒｏｂｉｎｓｏｎ介质（ｐＨ２．５）中研究了头孢唑啉的半微分吸附伏安法行为，并讨论了电极过程。在选定条件下，于－０．６７Ｖ（ｖｓ．Ａｇ／ＡｇＣｌ）处得一灵敏的还原峰。富集５０ｓ，其浓度在４．４×１０￣－９～１．１×１０￣－７ｍｏ１／Ｌ范围内与峰电流值呈良好线性关系，检测下限为２．２×１０￣－９ｍｏ１／Ｌ方法无需前处理即可用于尿液及血清样品中痕量头孢唑啉的测定，回收率在９２．５％～１０８．３％，相对标准偏差为２．８％。
he semidifferential adsorptive strppingvoltammetric behaviour of cefazolin has beenstudied in the medium of Britton-Robinsonbuffer solution(pH2.5 )and the mechanism ofits electrode process has been discussed.In op-timum conditions,a sensitive reduction peak ofcefazolin may be observed at the potential-0. 67V(vs.Ag/AgCl).Its peak current var-ied linearly with the concentration in the rangeof.4×10￣-9～1.1×10￣-7mol/L,when it waspreconcentrated for 50 seconds,the detectionhmit was 2.3×10￣-9mol/L. This method wassatkfactorv for the determination of trace cefa-zolin in urine and blood serum samples withoutPretreatment.Its recovery was 92.5%～108. 3%and its relative standard deviation was2. 8%.
出处
《分析试验室》
CAS
CSCD
北大核心
1996年第4期20-24,共5页
Chinese Journal of Analysis Laboratory
基金
浙江省自然科学基金
关键词
头孢唑啉
抗菌素
吸附伏安法
Cefazolin
antibiotics
semidif-fential adsorptive voltammetry
