摘要
目的：研究芩栀胶囊（黄芩、栀子）的抗病毒和抗菌作用。方法：采用体内实验方法，观察芩栀胶囊对病毒或细菌感染小鼠的保护作用；采用体外实验方法，测定芩栀胶囊的抗菌活性。结果：芩栀胶囊可明显延长甲、乙型流感病毒、金黄色葡萄球菌、肺炎双球菌感染小鼠的存活天数（P〈0．05或P〈0．01），提高感染小鼠存活率（P〈0．05）；可明显逆转感染小鼠的肺炎性病变；对17种细菌具有较强的抑菌作用，MIC在12．5—100mg（生药）／mL之间。结论：芩栀胶囊具有明显的抗病毒和抗菌作用。
AIM： To study Qinzhi Capsule （Radix Scutellaniae, Fructus Gardeniae） against virus and bacteria. METHODS： The mice were infected separately by Ⅰ , Ⅱ type flu virus, staphylococcus aureus or pneumococcus in the experiment. The protective action of Qinzhi Capsule on them was observed in vivo. and detemined mininum inhibition concettation （MIC）. RESULTS ： Qinzhi Capsule could prolong markedly the survival periods of mice （P 〈 0.05 or P 〈 0.01 ）, enhance their survival rates （ P 〈 0.05 ）, and reverse evidently their pneumonia pathological changes. The MIC of Qinzhi Capsule was 12.5 -100 mg（crude medicinal materials）/ml to seventeen bacteria. CONCLUSION： Qinzhi Capsule possesses the anti-virus and anti-bacteria effects.
出处
《中成药》
CAS
CSCD
北大核心
2006年第2期225-228,共4页
Chinese Traditional Patent Medicine
基金
扬子江药业集团新药研究基金资助.
