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一氧化氮及诱导型一氧化氮合酶与早产儿脑室周围白质软化 被引量:2

Nitric Oxide, Inducible Nitric Oxide Synthase and Periventricular Leukomalacia in Prematures
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摘要 脑室周围白质软化是早产儿脑白质损伤中最主要的类型之一,脑缺氧缺血和宫内感染被认为是其发病的两大因素。脑缺氧缺血和宫内感染均可使患儿体内的细胞因子水平增高并激活,启动脑组织中诱导型一氧化氮合酶的大量表达,从而产生过量的一氧化氮发挥神经毒性作用,其中心环节在于一氧化氮对少突胶质细胞前体细胞的损伤作用。
作者 沈盈 俞惠民
出处 《国际儿科学杂志》 2006年第1期55-57,共3页 International Journal of Pediatrics
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