摘要
目的了解西安地区饮食、公共场所从业人群甲肝急性感染状况,为制定西安市规范体检体系提供依据.方法采用酶联免疫吸附试验(ELISA)法检测1999～2003年西安地区饮食行业、公共场所的从业人员体检者血清中甲肝抗体(HAV-IgM),结果判定参照中华人民共和国国家标准GB 17010-1997.结果 1999～2003年西安市共体检了213 052人,累计发现HAV-IgM阳性114人,抗体阳性率为53.5/10万,不同年度间抗体阳性率波动在14.57/10万～88.72/10万间,经χ2检验年度间抗体阳性率差异非常显著(χ2=21.305 2,P＜0.01).平均阳性率(53.5/10万)与西安市甲肝总发病率和年龄发病率比较相对危险性(OR)分别为1.95和4.90倍.结论表明我市从业人员中有较高的甲肝抗体阳性检出率.提示此类人群作为传染源的可能性极大,应加强此类人群管理,杜绝甲肝食源性传播.
[Objective]To learn the situation of the acute infection of HAV and provide basis for physical examination system. [Methods] ELISA was applied to detect the HAV- IgM in the serum of staff working in public places between 1999 to 2003; the result was judged according to the national standard of GB 17010 - 1997. [Results]Among the 213052 examined cases, a total of 114 cases were found with HAV- IgM; the positive rate was 53.5/100000. Significant difference was found between annual positive rates （χ^2 = 21.3052, P 〈 0.01）. The OR was 1.95 times and 4.90 times respectively when the average positive rate （53.5/100000） is compared with the total morbidity and the age morbidity of HAV. [ Conclusion ] The positive detection rate of HAV - IgM is relatively high in this city, which indicates a large possibility of source of infection; management should be strengthened in order to put an end to the spread of HAV through food.
出处
《职业与健康》
CAS
2005年第12期2012-2013,共2页
Occupation and Health
