摘要
目的了解2014—2017年盐城市盐都区食品、公共场所从业人员甲型肝炎(甲肝)和戊型肝炎(戊肝)感染状况,为有针对性地做好急性肠道传染病预防控制工作提供依据。方法对2014—2017年在盐城市盐都区疾病预防控制中心进行健康检查的食品和公共场所从业人员采取静脉血液检测甲肝、戊肝免疫球蛋白M(IgM)抗体,并结合血清丙氨酸氨基转移酶(ALT)项目分析。结果从业人员中甲肝、戊肝IgM抗体阳性率分别为0.05%(28/51 317)、0.15%(79/51 317),戊肝IgM抗体阳性率高于甲肝IgM抗体(χ~2=24.334,P<0.01),无重叠感染。男女性别之间甲肝、戊肝IgM抗体阳性率及总阳性率比较差异均无统计学意义(P>0.05)。甲肝IgM抗体阳性率和戊肝IgM抗体阳性率均有着随年龄增长而上升的趋势(χ~2趋势(甲肝)=8.050,χ~2趋势(戊肝)=24.790,均P<0.01)。甲肝、戊肝IgM抗体阳性从业人员中ALT异常率分别为7.14%(2/28)和3.80%(3/79);2个月左右后甲肝、戊肝IgM抗体阴转率为61.54%(8/13)和46.34%(19/41)。结论 2014—2017年盐城市盐都区食品和公共场所从业人员甲肝、戊肝IgM抗体阳性存在一定比例,特别是戊肝,且绝大多数是隐匿性感染,2个月后复检结果,阳性比例较高,需引起卫生行政部分和卫生防病人员重视,需采取一定措施,有效遏制甲肝、戊肝等肠道急性传染性肝炎传播。
[Objective]To provide scientific basis for preventing and controlling the acute intestinal infectious diseases by analyzing the infection status of hepatitis A(HAV)and hepatitis E(HEV)among employees in food industry and public place in Yandu District of Yancheng City from 2014-2017.[Methods]The venous blood samples were collected from the employees in food industry and public place,who received the health examination in Yandu District Center for Disease Control and Prevention of Yancheng City from 2014-2017,to detect the anti-HAV and anti-HEV IgM,and were analyzed with alanine aminotransferase(ALT).[Results]Among the employees,the positive rate of anti-HAV and anti-HEV IgM was 0.05%(28/51 317)and 0.15%(79/51 317)respectively,and the positive rate of anti-HEV IgM was higher than that of anti-HAV IgM(χ^2=24.334,P<0.01).No people were infected both HAV and HEV.There were no statistically significant differences in the total positive rate and total positive rate of anti-HAV and anti-HEV IgM between males and females(P>0.05).The positive rates of anti-HAV and anti-HEV IgM showed a rising trend with age(χ^2 trend(HAV)=8.050,χ^2 trend(HEV)=24.790,both P<0.01).Among employees with positive anti-HAV and anti-HEV IgM,the abnormal rate was 7.14%(2/28)and 3.80%(3/79)respectively.The negative conversion rate of anti-HAV and anti-HEV IgM was respectively 61.54%(8/13)and 46.34%(19/41)after two months.[Conclusion]There is a certain proportion of positive anti-HAV and anti-HEV IgM among employees in food industry and public place in Yandu District of Yancheng City from 2014-2017,especially the HEV,and most of them are occult infections.The positive rate is higher in the reexamination after two months late.The health administrative departments and health prevention personnel should pay attention to this problem,and take certain measures to effectively curb the spread of acute intestinal tract infectious hepatitis A and hepatitis E.
作者
胥加耕
袁中行
刘庆勇
宋金卿
XU Jia-geng;YUAN Zhong-hang;LIU Qing-yong;SONG Jin-qing(Clinical Laboratory,Yandu District Center fo.r Disease Control and Prevention of Yancheng City,Yancheng Jiangsu,224001,China)
出处
《职业与健康》
CAS
2019年第1期61-64,共4页
Occupation and Health
