摘要
目的:通过对1992～2000年梅毒的临床治疗方法及随访结果回顾性对比分析,以选择最佳有效药物.方法:1 516例梅毒按统一标准进行诊断和6种抗生素选择治疗,使用统一的登记表格,由性病专科医生统一填写,汇总、统计和分析.结果:治疗早期梅毒青霉素治愈率平均达92.30%,头孢曲松钠、米诺环素、多西环素和阿奇霉素治愈率分别为90.13%、87.38%、87.88%和68.54%.青霉素与各组间治愈率对比统计学处理差异有显著性(P＜0.05).结论:青霉素治疗梅毒仍是首选,且疗效高、价格低.头孢曲松钠、米诺环素、多西环素则是有效的驱梅替代药物.
Objective： To select the brest valid medicine which can cure the early syphilis fast and thoroughly, provide comprehensive clinical information ＇after the comparative analysis of clinical therapy and restdts of follow-up in syphilis cases from 1992 to 2000. Methods： 1516 syphilis cases were diaoiosed and treated with different kind of six antibiotics based on the same standard.The specialists of venereal diseases statistically calculated and analyzed the results on the filled registers. Results： Penicillin cure rate was 92.30%. The cure rates of ceftriaxone sodium, minocycline, doxycycline and azithromycin were 90.13%, 87.38%, 87.88% and 68.54% respectively. The difference in the cure rate between penicillin and other 5 antibiotics applied had statistical significance （ P〈0.05 ）. Conclusion： Penicillin is still the first choice to treat syphilis with curative effect and low price. Cefiriaxone sodium, minoeycline, doxycycline are valid alternative medicines for syphilis.
出处
《中国麻风皮肤病杂志》
2005年第10期785-787,共3页
China Journal of Leprosy and Skin Diseases
